Yes, this one a rat paper found higher NO levels in the ketogenic diet-fed rat group vs the regular chow rat group. The authors think the increased NO on a ketogenic diet may explain why it’s helps with epilepsy.
This other rat paper also found higher NO in the 4-week ketogenic diet fed rat group vs the regular chow control group. The found NO to be higher in the hippocampus specifically and that increased neuronal synthesis of NO was the origin of the increased NO on the ketogenic diet.
A ketogenic diet usually is much lower in fructose than a SAD or other modern diet. Fructose is metabolized in the liver, raising uric acid and lowering NO. The ketogenic can raise NO and because fructose is present in small quantities in a typical ketogenic diet, lower the fructose derived uric acid production. Hence, the ketogenic is well geared towards normalizing blood pressure and lessening the liver’s burden to metabolize elements like fructose which are easily consumed in excessively high quantities nowadays.